USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: NDUS3_HUMAN USC-OGP 2-DE database:  NDUS3_HUMAN NDUS3_HUMAN General information about the entry View entry in simple text format Entry name NDUS3_HUMAN Primary accession number O75489 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial; EC=1.6.5.3; EC=1.6.99.3; AltName: Full=Complex I-30kD; Short=CI-30kD; AltName: Full=NADH-ubiquinone oxidoreductase 30 kDa subunit; Flags: Precursor;. Gene name Name=NDUFS3 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1275: pI=5.05; Mw=27445 SPOT OGP-1276: pI=5.55; Mw=27445 Cross-references UniProtKB/Swiss-Prot O75489; NDUS3_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name NDUS3_HUMAN Primary accession number O75489 Secondary accession number(s) B2R9J1 B4DFM8 Q9UNQ8 Sequence was last modified on  November 1, 1998 (version 1) Annotations were last modified on  March 15, 2017 (version 169) Name and origin of the protein Description RecName: Full=NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial; EC=1.6.5.3; EC=1.6.99.3; AltName: Full=Complex I-30kD; Short=CI-30kD; AltName: Full=NADH-ubiquinone oxidoreductase 30 kDa subunit; Flags: Precursor; Gene name Name=NDUFS3 Encoded on Name=NDUFS3 Keywords Alternative splicing; Complete proteome; Direct protein sequencing; Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane; NAD; Oxidoreductase; Polymorphism; Reference proteome; Respiratory chain; Transit peptide; Transport; Ubiquinone. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF067139; AAC27451.1; -; mRNA EMBL AF200954; AAG17541.1; -; Genomic_DNA EMBL AF100743; AAD40386.1; -; mRNA EMBL AK294167; BAG57489.1; -; mRNA EMBL AK313802; BAG36538.1; -; mRNA EMBL AC090559; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AC104942; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471064; EAW67895.1; -; Genomic_DNA EMBL BC000617; AAH00617.1; -; mRNA CCDS CCDS7941.1; -. [O75489-1]; . PIR JE0195; JE0195; . RefSeq NP_004542.1; NM_004551.2. [O75489-1]; . UniGene Hs.502528; -; . ProteinModelPortal O75489; -; . SMR O75489; -; . BioGrid 110801; 153; . IntAct O75489; 51; . MINT MINT-3001344; -; . STRING 9606.ENSP00000263774; -; . ChEMBL CHEMBL2363065; -; . DrugBank DB00997; Doxorubicin; . DrugBank DB00157; NADH; . iPTMnet O75489; -; . PhosphoSitePlus O75489; -; . SwissPalm O75489; -; . BioMuta NDUFS3; -; . REPRODUCTION-2DPAGE IPI00025796; -; . REPRODUCTION-2DPAGE O75489; -; . EPD O75489; -; . MaxQB O75489; -; . PaxDb O75489; -; . PeptideAtlas O75489; -; . PRIDE O75489; -; . TopDownProteomics O75489-1; -. [O75489-1]; . DNASU 4722; -; . Ensembl ENST00000263774; ENSP00000263774; ENSG00000213619. [O75489-1]; . Ensembl ENST00000534716; ENSP00000434970; ENSG00000213619. [O75489-2]; . GeneID 4722; -; . KEGG hsa:4722; -; . UCSC uc001nga.3; human. [O75489-1]; . CTD 4722; -; . DisGeNET 4722; -; . GeneCards NDUFS3; -; . HGNC HGNC:7710; NDUFS3; . HPA HPA004484; -; . MalaCards NDUFS3; -; . MIM 603846; gene; . neXtProt NX_O75489; -; . OpenTargets ENSG00000213619; -; . Orphanet 2609; Isolated NADH-CoQ reductase deficiency; . Orphanet 255241; Leigh syndrome with leukodystrophy; . PharmGKB PA31520; -; . eggNOG KOG1713; Eukaryota; . eggNOG COG0852; LUCA; . GeneTree ENSGT00390000017480; -; . HOGENOM HOG000009797; -; . HOVERGEN HBG000450; -; . InParanoid O75489; -; . KO K03936; -; . OMA AECLPKY; -; . OrthoDB EOG091G0AFP; -; . PhylomeDB O75489; -; . TreeFam TF314794; -; . Reactome R-HSA-611105; Respiratory electron transport; . Reactome R-HSA-6799198; Complex I biogenesis; . ChiTaRS NDUFS3; human; . GeneWiki NDUFS3; -; . GenomeRNAi 4722; -; . PRO PR:O75489; -; . Proteomes UP000005640; Chromosome 11; . Bgee ENSG00000213619; -; . CleanEx HS_NDUFS3; -; . ExpressionAtlas O75489; baseline and differential; . Genevisible O75489; HS; . GO GO:0005759; C:mitochondrial matrix; TAS:Reactome; . GO GO:0031966; C:mitochondrial membrane; IDA:UniProtKB; . GO GO:0005747; C:mitochondrial respiratory chain complex I; IDA:UniProtKB; . GO GO:0005739; C:mitochondrion; NAS:UniProtKB; . GO GO:0043209; C:myelin sheath; IEA:Ensembl; . GO GO:0016604; C:nuclear body; IDA:HPA; . GO GO:0009055; F:electron carrier activity; NAS:UniProtKB; . GO GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB; . GO GO:0003954; F:NADH dehydrogenase activity; IMP:UniProtKB; . GO GO:0045333; P:cellular respiration; IBA:GO_Central; . GO GO:0006120; P:mitochondrial electron transport; NADH to ubiquinone; NAS:UniProtKB GO GO:0032981; P:mitochondrial respiratory chain complex I assembly; TAS:Reactome; . GO GO:0030308; P:negative regulation of cell growth; IMP:UniProtKB; . GO GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB; . GO GO:0072593; P:reactive oxygen species metabolic process; IMP:UniProtKB; . GO GO:0021762; P:substantia nigra development; IEP:UniProtKB; . HAMAP MF_01357; NDH1_NuoC; 1; . InterPro IPR010218; NADH_DH_suC; . InterPro IPR001268; NADH_UbQ_OxRdtase_30kDa_su; . InterPro IPR020396; NADH_UbQ_OxRdtase_CS; . Pfam PF00329; Complex1_30kDa; 1; . ProDom PD001581; NADH_UbQ_OxRdtase_30kDa_su; 1; . TIGRFAMs TIGR01961; NuoC_fam; 1; . PROSITE PS00542; COMPLEX1_30K; 1; .

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• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
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• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
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